Compared with the results of dma direct sequencing, pcr-sscp has the same results as that except for failing to check out the rpob gene mutation of a rifampin-resistant isolate . it proves that pcr-sscp is a rapid and sensitive mutation testing method 与dna测序结果相比较,pcr-sscp除一个耐药株的rpob基因突变没有检出外,其它检测结果均与dna测序结果相一致,这进一步说明pcr-sscp是一种快速、灵敏的突变检测技术。